Human ABCB5(ATP Binding Cassette Transporter B5) ELISA Kit
 Polyclonal Antibody (Human), APC) ATP Binding Cassette Transporter B5 (ABCB5) Polyclonal Antibody (Human), APC |
|
4-PAD635Hu01-APC |
Cloud-Clone |
-
EUR 414.00
-
EUR 3930.00
-
EUR 1094.40
-
EUR 528.00
-
EUR 262.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
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|
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Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter B5 (ABCB5). This antibody is labeled with APC. |
 Polyclonal Antibody (Human), Cy3) ATP Binding Cassette Transporter B5 (ABCB5) Polyclonal Antibody (Human), Cy3 |
|
4-PAD635Hu01-Cy3 |
Cloud-Clone |
-
EUR 502.80
-
EUR 5190.00
-
EUR 1410.00
-
EUR 654.00
-
EUR 301.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
|
|
Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter B5 (ABCB5). This antibody is labeled with Cy3. |
 Polyclonal Antibody (Human), FITC) ATP Binding Cassette Transporter B5 (ABCB5) Polyclonal Antibody (Human), FITC |
|
4-PAD635Hu01-FITC |
Cloud-Clone |
-
EUR 355.20
-
EUR 3168.00
-
EUR 900.00
-
EUR 446.40
-
EUR 234.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
|
|
Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter B5 (ABCB5). This antibody is labeled with FITC. |
 Polyclonal Antibody (Human), HRP) ATP Binding Cassette Transporter B5 (ABCB5) Polyclonal Antibody (Human), HRP |
|
4-PAD635Hu01-HRP |
Cloud-Clone |
-
EUR 379.20
-
EUR 3426.00
-
EUR 968.40
-
EUR 477.60
-
EUR 247.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
|
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Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter B5 (ABCB5). This antibody is labeled with HRP. |
 Polyclonal Antibody (Human), Biotinylated) ATP Binding Cassette Transporter B5 (ABCB5) Polyclonal Antibody (Human), Biotinylated |
|
4-PAD635Hu01-Biotin |
Cloud-Clone |
-
EUR 373.20
-
EUR 2952.00
-
EUR 872.40
-
EUR 457.20
-
EUR 262.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
|
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Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter B5 (ABCB5). This antibody is labeled with Biotin. |
 Polyclonal Antibody (Human), APC-Cy7) ATP Binding Cassette Transporter B5 (ABCB5) Polyclonal Antibody (Human), APC-Cy7 |
|
4-PAD635Hu01-APC-Cy7 |
Cloud-Clone |
-
EUR 685.20
-
EUR 7716.00
-
EUR 2046.00
-
EUR 912.00
-
EUR 382.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
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|
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Description: A Rabbit polyclonal antibody against Human ATP Binding Cassette Transporter B5 (ABCB5). This antibody is labeled with APC-Cy7. |
 Protein) Human ATP Binding Cassette Transporter B7 (ABCB7) Protein |
|
20-abx650381 |
Abbexa |
-
EUR 710.40
-
EUR 309.60
-
EUR 2131.20
-
EUR 844.80
-
EUR 526.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Human ATP Binding Cassette Transporter B8 (ABCB8) Protein |
|
20-abx650383 |
Abbexa |
-
EUR 861.60
-
EUR 343.20
-
EUR 2698.80
-
EUR 1028.40
-
EUR 610.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Human ATP Binding Cassette Transporter B9 (ABCB9) Protein |
|
20-abx650386 |
Abbexa |
-
EUR 727.20
-
EUR 309.60
-
EUR 2180.40
-
EUR 861.60
-
EUR 526.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody) ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx225001 |
Abbexa |
-
EUR 444.00
-
EUR 727.20
-
EUR 376.80
|
|
|
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ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx242244 |
Abbexa |
|
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ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx242245 |
Abbexa |
|
|
|
|
 Antibody) ATP Binding Cassette Transporter B7 (ABCB7) Antibody |
|
20-abx241167 |
Abbexa |
|
|
|
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ATP Binding Cassette Transporter B7 (ABCB7) Antibody |
|
20-abx241168 |
Abbexa |
|
|
|
|
 Antibody) ATP Binding Cassette Transporter B4 (ABCB4) Antibody |
|
20-abx110010 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
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ATP Binding Cassette Transporter B7 (ABCB7) Antibody |
|
20-abx324585 |
Abbexa |
|
|
|
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ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx322557 |
Abbexa |
|
|
|
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ATP Binding Cassette Transporter B7 (ABCB7) Antibody |
|
20-abx333952 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B7 (ABCB7) Antibody |
|
abx330588-100ul |
Abbexa |
100 ul |
EUR 510 |
|
|
ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
abx038131-100ug |
Abbexa |
100 ug |
EUR 469.2 |
|
|
ATP Binding Cassette Transporter B4 (ABCB4) Antibody |
|
20-abx130561 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1479.60
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B7 (ABCB7) Antibody |
|
20-abx130563 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1479.60
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B7 (ABCB7) Antibody |
|
20-abx130564 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1446.00
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx130565 |
Abbexa |
-
EUR 543.60
-
EUR 159.60
-
EUR 1562.40
-
EUR 744.00
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx130566 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1479.60
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx130567 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1446.00
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody) ATP Binding Cassette Transporter B9 (ABCB9) Antibody |
|
20-abx130568 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1479.60
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B9 (ABCB9) Antibody |
|
20-abx130569 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1446.00
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B4 (ABCB4) Antibody |
|
20-abx334071 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx321079 |
Abbexa |
|
|
|
|
ATP Binding Cassette Transporter B9 (ABCB9) Antibody |
|
20-abx339444 |
Abbexa |
|
|
|
|
ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
abx432263-200ul |
Abbexa |
200 ul |
EUR 343.2 |
|
|
ATP Binding Cassette Transporter B8 (ABCB8) Antibody |
|
20-abx005962 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
|
) Recombinant ATP Binding Cassette Transporter B10 (ABCB10) |
|
4-RPD640Hu01 |
Cloud-Clone |
-
EUR 509.22
-
EUR 260.40
-
EUR 1579.58
-
EUR 606.53
-
EUR 1093.06
-
EUR 416.40
-
EUR 3768.96
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human ATP Binding Cassette Transporter B10 expressed in: E.coli |
Recombinant ATP Binding Cassette Transporter B10 (ABCB10) |
|
4-RPD640Mu01 |
Cloud-Clone |
-
EUR 541.48
-
EUR 268.80
-
EUR 1700.54
-
EUR 646.85
-
EUR 1173.70
-
EUR 438.00
-
EUR 4071.36
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse ATP Binding Cassette Transporter B10 expressed in: E.coli |
) Recombinant ATP Binding Cassette Transporter B11 (ABCB11) |
|
4-RPD641Hu01 |
Cloud-Clone |
-
EUR 532.87
-
EUR 266.40
-
EUR 1668.29
-
EUR 636.10
-
EUR 1152.19
-
EUR 432.00
-
EUR 3990.72
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human ATP Binding Cassette Transporter B11 expressed in: E.coli |
Recombinant ATP Binding Cassette Transporter B11 (ABCB11) |
|
4-RPD641Mu01 |
Cloud-Clone |
-
EUR 593.09
-
EUR 282.00
-
EUR 1894.08
-
EUR 711.36
-
EUR 1302.72
-
EUR 472.80
-
EUR 4555.20
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse ATP Binding Cassette Transporter B11 expressed in: E.coli |
) Recombinant ATP Binding Cassette Transporter B4 (ABCB4) |
|
4-RPD634Mu01 |
Cloud-Clone |
-
EUR 535.03
-
EUR 266.40
-
EUR 1676.35
-
EUR 638.78
-
EUR 1157.57
-
EUR 433.20
-
EUR 4010.88
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse ATP Binding Cassette Transporter B4 expressed in: E.coli |
) Recombinant ATP Binding Cassette Transporter B6 (ABCB6) |
|
4-RPD636Hu01 |
Cloud-Clone |
-
EUR 513.53
-
EUR 260.40
-
EUR 1595.71
-
EUR 611.90
-
EUR 1103.81
-
EUR 418.80
-
EUR 3809.28
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human ATP Binding Cassette Transporter B6 expressed in: E.coli |
) Recombinant ATP Binding Cassette Transporter B7 (ABCB7) |
|
4-RPD637Hu01 |
Cloud-Clone |
-
EUR 509.22
-
EUR 260.40
-
EUR 1579.58
-
EUR 606.53
-
EUR 1093.06
-
EUR 416.40
-
EUR 3768.96
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human ATP Binding Cassette Transporter B7 expressed in: E.coli |
Recombinant ATP Binding Cassette Transporter B7 (ABCB7) |
|
4-RPD637Mu01 |
Cloud-Clone |
-
EUR 541.48
-
EUR 268.80
-
EUR 1700.54
-
EUR 646.85
-
EUR 1173.70
-
EUR 438.00
-
EUR 4071.36
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse ATP Binding Cassette Transporter B7 expressed in: E.coli |
) Recombinant ATP Binding Cassette Transporter B8 (ABCB8) |
|
4-RPD638Hu01 |
Cloud-Clone |
-
EUR 623.20
-
EUR 290.40
-
EUR 2006.98
-
EUR 748.99
-
EUR 1377.98
-
EUR 492.00
-
EUR 4837.44
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human ATP Binding Cassette Transporter B8 expressed in: E.coli |
Recombinant ATP Binding Cassette Transporter B8 (ABCB8) |
|
4-RPD638Mu01 |
Cloud-Clone |
-
EUR 567.29
-
EUR 274.80
-
EUR 1797.31
-
EUR 679.10
-
EUR 1238.21
-
EUR 454.80
-
EUR 4313.28
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse ATP Binding Cassette Transporter B8 expressed in: E.coli |
Recombinant ATP Binding Cassette Transporter B8 (ABCB8) |
|
4-RPD638Ra01 |
Cloud-Clone |
-
EUR 578.04
-
EUR 278.40
-
EUR 1837.63
-
EUR 692.54
-
EUR 1265.09
-
EUR 462.00
-
EUR 4414.08
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat ATP Binding Cassette Transporter B8 expressed in: E.coli |
) Recombinant ATP Binding Cassette Transporter B9 (ABCB9) |
|
4-RPD639Hu01 |
Cloud-Clone |
-
EUR 517.82
-
EUR 261.60
-
EUR 1611.84
-
EUR 617.28
-
EUR 1114.56
-
EUR 422.40
-
EUR 3849.60
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human ATP Binding Cassette Transporter B9 expressed in: E.coli |
Recombinant ATP Binding Cassette Transporter B9 (ABCB9) |
|
4-RPD639Mu01 |
Cloud-Clone |
-
EUR 550.08
-
EUR 271.20
-
EUR 1732.80
-
EUR 657.60
-
EUR 1195.20
-
EUR 444.00
-
EUR 4152.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse ATP Binding Cassette Transporter B9 expressed in: E.coli |
 ELISA Kit) Human ABCC5(ATP Binding Cassette Transporter C5) ELISA Kit |
|
EH0475 |
FN Test |
96T |
EUR 628.92 |
|
|
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml |
 ELISA Kit) Human ABCG1(ATP Binding Cassette Transporter G1) ELISA Kit |
|
EH0476 |
FN Test |
96T |
EUR 628.92 |
|
|
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
 Protein) Rat ATP Binding Cassette Transporter B8 (ABCB8) Protein |
|
20-abx650385 |
Abbexa |
-
EUR 811.20
-
EUR 326.40
-
EUR 2481.60
-
EUR 961.20
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
) Human ATP Binding Cassette Transporter C2 ELISA Kit (ABCC2) |
|
RK00788 |
Abclonal |
96 Tests |
EUR 625.2 |
) Human ATP Binding Cassette Transporter C4 ELISA Kit (ABCC4) |
|
RK00789 |
Abclonal |
96 Tests |
EUR 625.2 |
) Human ATP Binding Cassette Transporter C5 ELISA Kit (ABCC5) |
|
RK00790 |
Abclonal |
96 Tests |
EUR 625.2 |
) Human ATP Binding Cassette Transporter C8 ELISA Kit (ABCC8) |
|
RK00791 |
Abclonal |
96 Tests |
EUR 625.2 |
) Human ATP Binding Cassette Transporter D1 ELISA Kit (ABCD1) |
|
RK00792 |
Abclonal |
96 Tests |
EUR 625.2 |
) Human ATP Binding Cassette Transporter G2 ELISA Kit (ABCG2) |
|
RK00793 |
Abclonal |
96 Tests |
EUR 625.2 |
 Antibody (HRP)) ATP Binding Cassette Transporter B4 (ABCB4) Antibody (HRP) |
|
20-abx336997 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B4 (ABCB4) Antibody (HRP) |
|
20-abx108518 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Antibody (HRP)) ATP Binding Cassette Transporter B7 (ABCB7) Antibody (HRP) |
|
20-abx334749 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Human ATP Binding Cassette Transporter G1 ELISA kit |
|
E01A0611-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human ATP Binding Cassette Transporter G1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human ATP Binding Cassette Transporter G1 ELISA kit |
|
E01A0611-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human ATP Binding Cassette Transporter G1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human ATP Binding Cassette Transporter G1 ELISA kit |
|
E01A0611-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A sandwich ELISA for quantitative measurement of Human ATP Binding Cassette Transporter G1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Human ATP Binding Cassette Transporter A1 ELISA kit |
|
E01A0631-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human ATP Binding Cassette Transporter A1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human ATP Binding Cassette Transporter A1 ELISA kit |
|
E01A0631-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human ATP Binding Cassette Transporter A1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human ATP Binding Cassette Transporter A1 ELISA kit |
|
E01A0631-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human ATP Binding Cassette Transporter A1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Antibody (FITC)) ATP Binding Cassette Transporter B4 (ABCB4) Antibody (FITC) |
|
20-abx107097 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
ATP Binding Cassette Transporter B4 (ABCB4) Antibody (FITC) |
|
20-abx336998 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Protein) Mouse ATP Binding Cassette Transporter B4 (ABCB4) Protein |
|
20-abx650379 |
Abbexa |
-
EUR 744.00
-
EUR 326.40
-
EUR 2264.40
-
EUR 895.20
-
EUR 543.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
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 Protein) Mouse ATP Binding Cassette Transporter B7 (ABCB7) Protein |
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20-abx650382 |
Abbexa |
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EUR 760.80
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EUR 326.40
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EUR 2298.00
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EUR 895.20
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EUR 543.60
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Human ABCB5(ATP Binding Cassette Transporter B5) ELISA Kit