Human CRBN(Cereblon) ELISA Kit
 ELISA Kit) Human Cereblon (CRBN) ELISA Kit |
|
RDR-CRBN-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 652.8 |
Human Cereblon (CRBN) ELISA Kit |
|
RDR-CRBN-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 907.2 |
 ELISA Kit) Mouse Cereblon (CRBN) ELISA Kit |
|
DLR-CRBN-Mu-48T |
DL Develop |
48T |
EUR 632.4 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cereblon (CRBN) in samples from tissue homogenates or other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
|
DLR-CRBN-Mu-96T |
DL Develop |
96T |
EUR 825.6 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cereblon (CRBN) in samples from tissue homogenates or other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
|
RD-CRBN-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Mouse Cereblon (CRBN) ELISA Kit |
|
RD-CRBN-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Mouse Cereblon (CRBN) ELISA Kit |
|
RDR-CRBN-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
Mouse Cereblon (CRBN) ELISA Kit |
|
RDR-CRBN-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 928.8 |
ELISA Kit) Human Cereblon (CRBN)ELISA Kit |
|
201-12-2889 |
SunredBio |
96 tests |
EUR 528 |
|
|
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
|
20-abx151037 |
Abbexa |
-
EUR 8853.60
-
EUR 4719.60
-
EUR 1093.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
Human Cereblon (CRBN) ELISA Kit |
|
SEG676Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5677.8 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
|
SEG676Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 572.76 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
|
SEG676Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 766.8 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
|
SEG676Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3090.6 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
|
4-SEG676Hu |
Cloud-Clone |
-
EUR 5738.40
-
EUR 3031.20
-
EUR 768.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Cereblon (CRBN) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
) Human Cereblon ELISA Kit (CRBN) |
|
RK01182 |
Abclonal |
96 Tests |
EUR 625.2 |
Mouse Cereblon (CRBN) ELISA Kit |
|
20-abx153810 |
Abbexa |
-
EUR 8853.60
-
EUR 4719.60
-
EUR 1093.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
Mouse Cereblon (CRBN) ELISA Kit |
|
SEG676Mu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5834.88 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
|
SEG676Mu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 585.7 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
|
SEG676Mu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 785.28 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
|
SEG676Mu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3173.76 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
|
4-SEG676Mu |
Cloud-Clone |
-
EUR 5895.60
-
EUR 3114.00
-
EUR 786.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Cereblon (CRBN) in samples from Tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species. |
 Human CRBN/ Protein cereblon ELISA Kit |
|
E0552Hu |
Sunlong |
1 Kit |
EUR 726 |
) ELISA kit for Human CRBN (Cereblon) |
|
ELK4870 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
|
|
Description: A sandwich ELISA kit for detection of Cereblon from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
 ELISA Kit) Human Protein cereblon (CRBN) ELISA Kit |
|
abx250736-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
|
 ELISA Kit) Human CRBN(Protein cereblon) ELISA Kit |
|
EH1457 |
FN Test |
96T |
EUR 681.12 |
|
|
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
 Antibody) Cereblon (CRBN) Antibody |
|
20-abx171671 |
Abbexa |
|
|
|
|
Cereblon (CRBN) Antibody |
|
20-abx175781 |
Abbexa |
|
|
|
|
Cereblon (CRBN) Antibody |
|
20-abx175782 |
Abbexa |
|
|
|
|
Cereblon (CRBN) Antibody |
|
20-abx175783 |
Abbexa |
|
|
|
|
Cereblon (CRBN) Antibody |
|
20-abx111556 |
Abbexa |
|
|
|
|
 CLIA Kit) Human Cereblon (CRBN) CLIA Kit |
|
20-abx495269 |
Abbexa |
-
EUR 9567.60
-
EUR 5095.20
-
EUR 1177.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
) Human Protein cereblon (CRBN) |
|
1-CSB-BP842761HU |
Cusabio |
-
EUR 913.20
-
EUR 367.20
-
EUR 2341.20
-
EUR 1231.20
-
EUR 1706.40
-
EUR 517.20
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in Baculovirus |
Human Protein cereblon (CRBN) |
|
1-CSB-CF842761HU |
Cusabio |
-
EUR 1158.00
-
EUR 798.00
-
EUR 858.00
|
|
|
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in in vitro E.coli expression system |
Human Protein cereblon (CRBN) |
|
1-CSB-CF842761HUa6 |
Cusabio |
-
EUR 1158.00
-
EUR 798.00
-
EUR 858.00
|
|
|
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in in vitro E.coli expression system |
Human Protein cereblon (CRBN) |
|
1-CSB-CF842761HUc7 |
Cusabio |
-
EUR 1158.00
-
EUR 798.00
-
EUR 858.00
|
|
|
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in in vitro E.coli expression system |
 Protein) Human Cereblon (CRBN) Protein |
|
20-abx652846 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
) ELISA kit for Mouse CRBN (Cereblon) |
|
ELK7246 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
|
|
Description: A sandwich ELISA kit for detection of Cereblon from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
 ELISA Kit) Cow Protein cereblon (CRBN) ELISA Kit |
|
abx516195-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
|
 ELISA Kit) Chicken Protein cereblon (CRBN) ELISA Kit |
|
abx516196-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
|
 ELISA Kit) Rat Protein cereblon (CRBN) ELISA Kit |
|
abx516199-96tests |
Abbexa |
96 tests |
EUR 886.8 |
|
|
 Chicken Protein cereblon, CRBN ELISA KIT |
|
ELI-25557c |
Lifescience Market |
96 Tests |
EUR 1113.6 |
 CLIA Kit) Mouse Cereblon (CRBN) CLIA Kit |
|
20-abx495270 |
Abbexa |
-
EUR 9567.60
-
EUR 5095.20
-
EUR 1177.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
) Mouse Protein cereblon (Crbn) |
|
1-CSB-YP806030MO |
Cusabio |
-
EUR 604.80
-
EUR 318.00
-
EUR 2198.40
-
EUR 915.60
-
EUR 1459.20
-
EUR 400.80
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Mouse Protein cereblon(Crbn) expressed in Yeast |
 Antibody) Protein Cereblon (CRBN) Antibody |
|
20-abx003568 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
|
Protein Cereblon (CRBN) Antibody |
|
abx200563-50ug |
Abbexa |
50 ug |
EUR 543.6 |
|
|
Protein Cereblon (CRBN) Antibody |
|
abx231954-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
|
 Protein) Mouse Cereblon (CRBN) Protein |
|
20-abx652847 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Mouse Cereblon (CRBN) Protein |
|
20-abx652848 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Protein Cereblon (CRBN) Antibody |
|
20-abx322665 |
Abbexa |
|
|
|
|
Protein Cereblon (CRBN) Antibody |
|
20-abx322666 |
Abbexa |
|
|
|
|
 Crbn ELISA Kit| Rat Protein cereblon ELISA Kit |
|
EF018463 |
Lifescience Market |
96 Tests |
EUR 826.8 |
 CRBN ELISA Kit| Bovine Protein cereblon ELISA Kit |
|
EF011221 |
Lifescience Market |
96 Tests |
EUR 826.8 |
 CRBN ELISA Kit| chicken Protein cereblon ELISA Kit |
|
EF012243 |
Lifescience Market |
96 Tests |
EUR 826.8 |
 Crbn ELISA Kit| Mouse Protein cereblon ELISA Kit |
|
EF014465 |
Lifescience Market |
96 Tests |
EUR 826.8 |
 Rabbit Polyclonal antibody Anti-CRBN |
|
Anti-CRBN |
ImmunoStep |
50 µg |
EUR 418.8 |
) Polyclonal CRBN / Cereblon Antibody (C-Terminus) |
|
APR11660G |
Leading Biology |
0.05mg |
EUR 580.8 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CRBN / Cereblon (C-Terminus). This antibody is tested and proven to work in the following applications: |
 (OKAN05721)) CRBN ELISA Kit (Human) (OKAN05721) |
|
OKAN05721 |
Aviva Systems Biology |
96 Wells |
EUR 950.4 |
|
Description: Description of target: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.057 ng/mL |
 (OKEH02269)) CRBN ELISA Kit (Human) (OKEH02269) |
|
OKEH02269 |
Aviva Systems Biology |
96 Wells |
EUR 794.4 |
|
Description: Description of target: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.2 ng/mL |
 (OKCD08967)) CRBN ELISA Kit (Human) (OKCD08967) |
|
OKCD08967 |
Aviva Systems Biology |
96 Wells |
EUR 1170 |
|
Description: Description of target: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutatio;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.057ng/mL |
 ELISA kit for Human Protein cereblon |
|
EK3125 |
SAB |
96 tests |
EUR 663.6 |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Protein cereblon in samples from serum, plasma, tissue homogenates and other biological fluids. |
 (OKCD02462)) CRBN ELISA Kit (Mouse) (OKCD02462) |
|
OKCD02462 |
Aviva Systems Biology |
96 Wells |
EUR 1028.4 |
|
Description: Description of target: Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8. May play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.057 ng/mL |
 (OKEH07882)) CRBN ELISA Kit (Bovine) (OKEH07882) |
|
OKEH07882 |
Aviva Systems Biology |
96 Wells |
EUR 1310.4 |
|
Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: |
 (OKEH07883)) CRBN ELISA Kit (Chicken) (OKEH07883) |
|
OKEH07883 |
Aviva Systems Biology |
96 Wells |
EUR 1420.8 |
|
Description: Description of target: ;Species reactivity: Chicken;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: |
 Cereblon Binding Assay Kit |
|
79899 |
BPS Bioscience |
96 rxns. |
EUR 600 |
|
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader. |
 Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed |
|
ELISA-1 |
Alpha Diagnostics |
1 |
EUR 242.4 |
 CRBN Antibody |
|
1-CSB-PA005944GA01HU |
Cusabio |
|
|
|
|
|
Description: A polyclonal antibody against CRBN. Recognizes CRBN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
CRBN Antibody |
|
1-CSB-PA842761ESR1HU |
Cusabio |
|
|
|
|
|
Description: A polyclonal antibody against CRBN. Recognizes CRBN from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
CRBN Antibody |
|
1-CSB-PA842761ESR2HU |
Cusabio |
|
|
|
|
|
Description: A polyclonal antibody against CRBN. Recognizes CRBN from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
 CRBN antibody |
|
70R-3211 |
Fitzgerald |
50 ug |
EUR 560.4 |
|
Description: Rabbit polyclonal CRBN antibody raised against the N terminal of CRBN |
CRBN antibody |
|
70R-16578 |
Fitzgerald |
50 ul |
EUR 522 |
|
Description: Rabbit polyclonal CRBN antibody |
 CRBN siRNA |
|
20-abx901245 |
Abbexa |
|
|
|
|
CRBN siRNA |
|
20-abx912756 |
Abbexa |
|
|
|
|
CRBN siRNA |
|
20-abx912757 |
Abbexa |
|
|
|
|
CRBN Antibody |
|
8115-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
|
|
Description: CRBN, a member of the Lon protease protein family, plays a role in brain development (1). It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8 (2). CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1. It is widely expressed and highly expressed in brain (3,4). |
CRBN Antibody |
|
8115-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
|
|
Description: CRBN, a member of the Lon protease protein family, plays a role in brain development (1). It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8 (2). CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1. It is widely expressed and highly expressed in brain (3,4). |
 CRBN Peptide |
|
8115P |
ProSci |
0.05 mg |
EUR 197.7 |
|
Description: CRBN Peptide |
 anti-CRBN |
|
YF-PA18916 |
Abfrontier |
50 ug |
EUR 435.6 |
|
Description: Mouse polyclonal to CRBN |
 Cereblon Ubiquitination Homogeneous Assay Kit |
|
79881 |
BPS Bioscience |
384 rxns. |
EUR 820 |
|
Description: The Cereblon Ubiquitination Homogeneous Assay Kit is designed to measure Cereblon auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled ubiquitin and proper A-screen beads to complete the pairing. This homogeneous assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. |
 Human CRBN shRNA Plasmid |
|
20-abx959590 |
Abbexa |
|
|
|
|
 CRBN Blocking Peptide |
|
DF12054-BP |
Affbiotech |
1mg |
EUR 234 |
 CRBN cloning plasmid |
|
CSB-CL842761HU1-10ug |
Cusabio |
10ug |
EUR 279.6 |
|
|
|
Description: A cloning plasmid for the CRBN gene. |
CRBN cloning plasmid |
|
CSB-CL842761HU2-10ug |
Cusabio |
10ug |
EUR 279.6 |
|
|
|
Description: A cloning plasmid for the CRBN gene. |
 anti- CRBN antibody |
|
FNab01954 |
FN Test |
100µg |
EUR 606.3 |
|
|
|
Description: Antibody raised against CRBN |
 CRBN Polyclonal Antibody |
|
30601-100ul |
SAB |
100ul |
EUR 302.4 |
CRBN Polyclonal Antibody |
|
30601-50ul |
SAB |
50ul |
EUR 224.4 |
CRBN Blocking Peptide |
|
33R-2125 |
Fitzgerald |
100 ug |
EUR 216 |
|
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CRBN antibody, catalog no. 70R-3211 |
 CRBN Rabbit pAb |
|
A4722-100ul |
Abclonal |
100 ul |
EUR 369.6 |
CRBN Rabbit pAb |
|
A4722-200ul |
Abclonal |
200 ul |
EUR 550.8 |
CRBN Rabbit pAb |
|
A4722-20ul |
Abclonal |
20 ul |
EUR 219.6 |
CRBN Rabbit pAb |
|
A4722-50ul |
Abclonal |
50 ul |
EUR 267.6 |
 Polyclonal CRBN Antibody |
|
APR11661G |
Leading Biology |
0.1 mg |
EUR 790.8 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CRBN . This antibody is tested and proven to work in the following applications: |
 Anti-CRBN antibody |
|
STJ26824 |
St John's Laboratory |
100 µl |
EUR 332.4 |
|
Description: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. |
 CRBN Assay Buffer |
|
79972 |
BPS Bioscience |
10 ml |
EUR 195 |
|
Description: The CRBN Assay Buffer is optimized for use with the Cereblon Binding Assay Kit (BPS Bioscience #79899). |
 Cereblon intrachain TR-FRET Assay Kit |
|
78301 |
BPS Bioscience |
384 rxns. |
EUR 1750 |
|
Description: Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications that regulates protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1), a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and efficiency of ubiquitination are largely determined by the E3 enzyme, which directs the last step of the Ub-conjugating cascade by binding to both an E2~Ub conjugate and a substrate protein. This step ensures the transfer of Ub from E2~Ub to the substrate, leading to its mono- or poly-ubiquitination.The Cereblon (CRBN) protein via its interaction with the DNA damage-binding protein-1 (DDB1), Cullin 4 (Cul4A or Cul4B), and regulator of Cullins 1 (RoC1) forms the functional E3 Ub ligase complex. In this complex, Cereblon functions as a substrate receptor that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Cereblon complex is involved in many biological processes including cell proliferation and apoptosis. That is why it has been employed for targeted protein degradation in the treatment of cancer. Like most E3 ligases, Cereblon complex ubiquitinates itself and this auto-ubiquitination promotes its Ub ligase activity.The Cereblon intrachain TR-FRET Assay Kit is a sensitive high-throughput screening (HTS) TR-FRET Assay Kit, designed to measure Cereblon auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes a Europium cryptate-labeled Ub (donor) as well as Cy5-labeled Ub (acceptor) to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains formed on Cereblon, this FRET-based assay requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time kinetics analyses of polyubiquitination. |
 (pORF)) CRBN ORF Vector (Human) (pORF) |
|
ORF002655 |
ABM |
1.0 ug DNA |
EUR 114 |
CRBN ORF Vector (Human) (pORF) |
|
ORF002656 |
ABM |
1.0 ug DNA |
EUR 114 |
 Cereblon, FLAG-Tag Recombinant |
|
100255-1 |
BPS Bioscience |
10 µg |
EUR 235 |
|
Description: Recombinant human cereblon (CRBN), full length, encompassing amino acids 2-422(end). This construct contains an N-terminal Flag-tag. The recombinant protein was affinity purified. |
Cereblon, FLAG-Tag Recombinant |
|
100255-2 |
BPS Bioscience |
50 µg |
EUR 595 |
|
Description: Recombinant human cereblon (CRBN), full length, encompassing amino acids 2-422(end). This construct contains an N-terminal Flag-tag. The recombinant protein was affinity purified. |
 Frit Kit |
|
FRIT-KIT |
Next Advance |
1each |
EUR 148.8 |
|
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool. |
 Column Packing Kit |
|
PACK-KIT |
Next Advance |
1pack |
EUR 1242 |
|
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar. |
 PCR Mycoplasma Detection Kit |
|
M034-Kit |
TOKU-E |
Kit |
EUR 319.2 |
 CRBN Polyclonal Conjugated Antibody |
|
C30601 |
SAB |
100ul |
EUR 476.4 |
 Rat CRBN shRNA Plasmid |
|
20-abx988863 |
Abbexa |
|
|
|
|
 Mouse CRBN shRNA Plasmid |
|
20-abx975104 |
Abbexa |
|
|
|
|
) CRBN sgRNA CRISPR Lentivector set (Human) |
|
K0504901 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
 Homo-PROTAC cereblon degrader 1 |
|
HY-111594 |
MedChemExpress |
10mg |
EUR 2126.4 |
 Cereblon/DDB1/Cul4A/Rbx1 Complex |
|
100329-1 |
BPS Bioscience |
10 µg |
EUR 255 |
|
Description: Cereblon/DDB1/Cul4A/Rbx1 complex of human Cereblon (GenBank Accession No. NM_016302) a.a. 2-442(end) with N-terminal FLAG-tag and MW= 51 kDa, human DDB1 (GenBank Accession No. NM_001923), a.a. 1-1140(end) with N-terminal FLAG-tag and MW= 128 kDa, human Cul4A (GenBank Accession No. NM_003589), a.a. 2-759(end) with N-terminal His-tag and MW= 87 kDa, human Rbx1 (GenBank Accession No. NM_014248), a.a. 2-108(end) with N-terminal His-tag and MW= 13 kDa, co-expressed in a HEK293 expression system. |
Cereblon/DDB1/Cul4A/Rbx1 Complex |
|
100329-2 |
BPS Bioscience |
50 µg |
EUR 640 |
|
Description: Cereblon/DDB1/Cul4A/Rbx1 complex of human Cereblon (GenBank Accession No. NM_016302) a.a. 2-442(end) with N-terminal FLAG-tag and MW= 51 kDa, human DDB1 (GenBank Accession No. NM_001923), a.a. 1-1140(end) with N-terminal FLAG-tag and MW= 128 kDa, human Cul4A (GenBank Accession No. NM_003589), a.a. 2-759(end) with N-terminal His-tag and MW= 87 kDa, human Rbx1 (GenBank Accession No. NM_014248), a.a. 2-108(end) with N-terminal His-tag and MW= 13 kDa, co-expressed in a HEK293 expression system. |
 Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit |
|
CAS400A-KIT |
SBI |
1 kit (10 rxn) |
EUR 1332 |
|
|
Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit |
|
CAS410A-KIT |
SBI |
1 kit (10 rxn) |
EUR 798 |
 Cas9-EGFP Protein and T7 gRNA SmartNuclease Synthesis Kit |
|
CAS420A-KIT |
SBI |
1 kit (10 rxn) |
EUR 828 |
 CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV100PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
 CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV105PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
 MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV120PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
 MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV125PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
 PROTAC® Optimization Kit for BRD9-Cereblon Binding |
|
78420 |
BPS Bioscience |
384 rxns. |
EUR 860 |
|
Description: The PROTAC Optimization Kit for BRD9-Cereblon Binding is designed for the testing and profiling of PROTACs directed against BRD9 and Cereblon (CRBN). The BRD9 inhibitor BI-7273 is included as a control inhibitor of PROTAC binding to BRD9. With this kit, three simple steps are required for the measurement of PROTAC activity. First, the PROTAC of interest is incubated with CRBN and BRD9. Next, acceptor beads are added, then donor beads, followed by reading of the Alpha-counts.Illustration of the assay principle: a PROTAC of interest or positive control dBRD9 (PROTAC) interacts with both BRD9 and CRBN, bringing them in close proximity. BRD9 contains a GST tag, recognized by the GSH donor bead, while CRBN contains a FLAG tag that binds to the AlphaLISA™ acceptor bead conjugated with an anti-FLAG antibody. Upon excitation of the donor bead a singlet oxygen is generated by the donor bead, which excites the acceptor bead and emits light proportionally to the level of interaction. AlphaLISA™ immunoassays are a no-wash alternative to ELISA immunoassays. These assays are robust and ideal for a minimal hands-on approach. |
 PROTAC® Optimization Kit for PARP1-Cereblon Binding |
|
78441 |
BPS Bioscience |
384 rxns. |
EUR 995 |
|
Description: The PROTAC Optimization Kit for PARP1-Cereblon Binding is designed for the testing and profiling of PROTACs directed against PARP1 and Cereblon (CRBN). This Kit comes in a convenient AlphaLISA™ format, with the PARP1 Degrader iRucaparib-AP6 (PROTAC) added as positive control, PARP1 buffer, purified PARP1 and CRBN proteins for 384 reactions. The PARP1 inhibitor Rucaparib is included as a control that blocks PROTAC binding to PARP1. With this kit, three simple steps are required for the measurement of PROTAC activity. First, the PROTAC of interest is incubated with CRBN and PARP1. Next, acceptor beads are added, then donor beads, followed by reading of the Alpha-counts.Illustration of the assay principle: A PROTAC of interest or positive control iRucaparib-AP6 (PROTAC) interacts with both PARP1 and CRBN, bringing them in close proximity. PARP1 contains a GST tag, recognized by the GSH donor bead, while CRBN contains a FLAG tag that binds to the AlphaLISA™ acceptor bead conjugated with an anti-FLAG antibody. Upon excitation of the donor bead, a singlet oxygen is generated by the donor bead. The singlet oxygen excites the acceptor bead and emits light proportionally to the level of interaction. AlphaLISA™ immunoassays are a no-wash alternative to ELISA immunoassays. These assays are robust and ideal for a minimal hands-on approach. |
 PROTAC® Optimization Kit for IRAK4-Cereblon Binding |
|
78512 |
BPS Bioscience |
384 rxns. |
EUR 860 |
|
Description: The PROTAC Optimization Kit for IRAK4-Cereblon Binding is designed for the testing and profiling of PROTACs directed against IRAK4 and Cereblon (CRBN). The IRAK4 ligand-1 is included as a control that blocks PROTAC binding to IRAK4. With this kit, only three simple steps are required for the measurement of PROTAC activity. First, the PROTAC of interest is incubated with CRBN and IRAK4. Next, acceptor beads are added, then donor beads, followed by reading of the Alpha-counts. Illustration of the assay principle: A PROTAC of interest or positive control IRAK4 Degrader-1 (PROTAC) interacts with both IRAK4 and CRBN, bringing them in close proximity. IRAK4 contains a GST-tag, recognized by the GSH donor bead, while CRBN contains a FLAG-tag that binds to the AlphaLISA™ acceptor bead conjugated with an anti-FLAG antibody. Upon excitation of the donor bead, a singlet oxygen is generated by the donor bead, which excites the acceptor bead and emits light proportionally to the level of interaction. AlphaLISA™ immunoassays are a no-wash alternative to ELISA immunoassays. These assays are robust and ideal for a minimal hands-on approach. |
 PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding |
|
79770 |
BPS Bioscience |
384 rxns. |
EUR 995 |
|
Description: The PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding is designed for testing and profiling of PROTACs directed against BET Bromodomain family and Cereblon complex. Cereblon (CRBN) is a Substrate recognition component of a DCX (DDB1-CUL44-Rbx1) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins._x000D_ The PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding comes in a convenient AlphaLISA® format, with dBET1 PROTAC, Immuno Buffer 1, and purified BRD3(BD2) and CRBN for 384 reactions. (+)JQ1 is included as a control inhibitor of PROTAC binding to BRD3(BD2). With this kit, only three simple steps on a microtiter plate are required for PROTAC activity detection. First, a sample containing PROTAC is incubated with CRBN and BRD3(BD2), one of BET bromodomains. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts._x000D_ |
 PROTAC Optimization Kit for CDK Kinase-Cereblon Binding |
|
79924 |
BPS Bioscience |
384 rxns. |
EUR 860 |
|
Description: The PROTAC Optimization Kit for CDK Kinase-Cereblon Binding is designed for testing and profiling of PROTACs directed against the CDK Kinase family and Cereblon. Cereblon (CRBN) is a Substrate recognition component of the DCX (DDB1-CUL44-Rbx1) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
The CDK inhibitor Palbociclib is included as a control inhibitor of PROTAC binding to CDK. With this kit, only three simple steps on a microtiter plate are required for PROTAC activity detection. First, a sample containing PROTAC is incubated with CRBN and CDK4 or CDK6 Kinase. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts. |
 Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector |
|
CAS700A-KIT |
SBI |
10 rxn |
EUR 1358.4 |
|
|
 Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector |
|
CAS720A-KIT |
SBI |
10 rxn |
EUR 1358.4 |
|
|
 Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector |
|
CAS740A-KIT |
SBI |
10 rxn |
EUR 1358.4 |
|
|
) T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents) |
|
CAS510A-KIT |
SBI |
1 Kit |
EUR 966 |
|
|
-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit) Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV200PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit) Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV205PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit) Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV220PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit) Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
|
CASLV225PA-KIT |
SBI |
1 Kit |
EUR 1358.4 |
|
|
 (Target 1)) CRBN sgRNA CRISPR Lentivector (Human) (Target 1) |
|
K0504902 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (Target 2)) CRBN sgRNA CRISPR Lentivector (Human) (Target 2) |
|
K0504903 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (Target 3)) CRBN sgRNA CRISPR Lentivector (Human) (Target 3) |
|
K0504904 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (pPB-C-His)) CRBN Protein Vector (Human) (pPB-C-His) |
|
PV010617 |
ABM |
500 ng |
EUR 394.8 |
 (pPB-N-His)) CRBN Protein Vector (Human) (pPB-N-His) |
|
PV010618 |
ABM |
500 ng |
EUR 394.8 |
 (pPM-C-HA)) CRBN Protein Vector (Human) (pPM-C-HA) |
|
PV010619 |
ABM |
500 ng |
EUR 394.8 |
 (pPM-C-His)) CRBN Protein Vector (Human) (pPM-C-His) |
|
PV010620 |
ABM |
500 ng |
EUR 394.8 |
CRBN Protein Vector (Human) (pPB-C-His) |
|
PV010621 |
ABM |
500 ng |
EUR 394.8 |
CRBN Protein Vector (Human) (pPB-N-His) |
|
PV010622 |
ABM |
500 ng |
EUR 394.8 |
CRBN Protein Vector (Human) (pPM-C-HA) |
|
PV010623 |
ABM |
500 ng |
EUR 394.8 |
CRBN Protein Vector (Human) (pPM-C-His) |
|
PV010624 |
ABM |
500 ng |
EUR 394.8 |
 Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector |
|
CAS750A-KIT |
SBI |
10 rxn |
EUR 1358.4 |
|
|
 Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector |
|
CAS770A-KIT |
SBI |
10 rxn |
EUR 1358.4 |
|
|
 Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector |
|
CAS790A-KIT |
SBI |
10 rxn |
EUR 1358.4 |
|
|
 (pORF)) Crbn ORF Vector (Rat) (pORF) |
|
ORF065411 |
ABM |
1.0 ug DNA |
EUR 607.2 |
 (pORF)) Crbn ORF Vector (Mouse) (pORF) |
|
ORF041971 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Crbn ORF Vector (Mouse) (pORF) |
|
ORF041972 |
ABM |
1.0 ug DNA |
EUR 607.2 |
) CRBN CRISPR/Cas9 Lentivirus (Integrating) |
|
78517 |
BPS Bioscience |
500 µl x 2 |
EUR 795 |
|
Description: Cereblon (CRBN) forms an E3 ubiquitin ligase complex which is responsible for ubiquitinating proteins that regulate various developmental processes. CRBN also binds to Calcium Activated Potassium Channel subunit alpha-1 (KCNMA1) to regulate ion transport. Moreover, mutations in CRBN may play an underlying role in tumor cells acquiring resistance to immunotherapy.The CRBN CRISPR/Cas9 Lentiviruses are replication incompetent, HIV-based VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a CRISPR/Cas9 gene driven by an EF1a promoter, along with 5 sgRNA (single guide RNA) targeting human CRBN.The DNA transduced by this lentivirus integrates randomly into the cellular genome to express both Cas9 and sgRNA. Puromycin selection increases the knockout efficiency by forcing high expression levels of both Cas9 and the sgRNA, and can be used with the integrating lentivirus to quickly and easily achieve high knockdown efficiencies in a cell pool. Efficiencies also depend on the cell type. |
 and Fast ligase (2.5ul)]) Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)] |
|
CAS9LIG-KIT |
SBI |
1 Kit |
EUR 183.6 |
|
|
 Recombinant Human Protein cereblon Protein, His, Baculovirus-100ug |
|
QP10056-ba-100ug |
EnQuireBio |
100ug |
EUR 1512 |
 Recombinant Human Protein cereblon Protein, His, Baculovirus-20ug |
|
QP10056-ba-20ug |
EnQuireBio |
20ug |
EUR 586.8 |
 Recombinant Human Protein cereblon Protein, His, Baculovirus-50ug |
|
QP10056-ba-50ug |
EnQuireBio |
50ug |
EUR 1098 |
) PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1) |
|
PIN320A-KIT |
SBI |
1 Kit |
EUR 5929.2 |
|
|
) PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1) |
|
PIN340iPS-KIT |
SBI |
1 Kit |
EUR 5929.2 |
|
|
, Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)) AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site) |
|
GE620A-KIT |
SBI |
1 kit |
EUR 2558.4 |
|
|
, Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)) AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site) |
|
GE622A-KIT |
SBI |
1 kit |
EUR 2558.4 |
|
|
, Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)) AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site) |
|
GE624A-KIT |
SBI |
1 kit |
EUR 2558.4 |
|
|
 Recombinant Human Protein cereblon Protein, His, Invitro-E.coli-100ug |
|
QP10011-iv-100ug |
EnQuireBio |
100ug |
EUR 1424.4 |
 Recombinant Human Protein cereblon Protein, His, Invitro-E.coli-10ug |
|
QP10011-iv-10ug |
EnQuireBio |
10ug |
EUR 554.4 |
 Recombinant Human Protein cereblon Protein, His, Invitro-E.coli-50ug |
|
QP10011-iv-50ug |
EnQuireBio |
50ug |
EUR 936 |
 Polyclonal CRBN antibody - N-terminal region |
|
APR11662G |
Leading Biology |
0.05mg |
EUR 633.6 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CRBN - N-terminal region. This antibody is tested and proven to work in the following applications: |
) Crbn sgRNA CRISPR Lentivector set (Mouse) |
|
K3487501 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
) Crbn sgRNA CRISPR Lentivector set (Rat) |
|
K6667501 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
 [His]) Recombinant CRBN Protein (Met1-Leu442) [His] |
|
VAng-Cr3790-inquire |
Creative Biolabs |
inquire |
Ask for price |
|
Description: Recombinant CRBN Protein (Met1-Leu442) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 48.62 kDa. (Uniprot ID: Q96SW2) |
) CRBN CRISPR/Cas9 Lentivirus (Non-Integrating) |
|
78518 |
BPS Bioscience |
500 µl x 2 |
EUR 995 |
|
Description: Cereblon (CRBN) forms an E3 ubiquitin ligase complex which is responsible for ubiquitinating proteins that regulate various developmental processes. CRBN also binds to Calcium Activated Potassium Channel subunit alpha-1 (KCNMA1) to regulate ion transport. Moreover, mutations in CRBN may play an underlying role in tumor cells acquiring resistance to immunotherapy.The CRBN CRISPR/Cas9 Lentiviruses are replication incompetent, HIV-based VSV-G pseudo-typed lentiviral particles that are ready to transduce into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a CRISPR/Cas9 gene driven by an EF1a promoter, along with 5 sgRNA (single guide RNA) targeting human CRBN.The non-integrating lentivirus is made with a mutated integrase, resulting in only transient expression of the Cas9 and sgRNA. Although using the non-integrating lentivirus results in lower knockdown efficiency, the Cas9 is not permanently expressed, which lowers the risk of off-targeting, and there are no random integrations into the cell's genome. Knockout cell lines can still be generated following cell sorting or limited dilution, because even though the Cas9 and sgRNA expression is transient, the changes in the genomic DNA from the Cas9 nuclease activity and NHEJ repair are permanent. |
 vWF Acty. Kit |
|
ABP-ACT-KIT |
Abpcorp |
12 x 8 microwells |
EUR 513.6 |
 vWF Ant. Kit |
|
ABP-TOT-KIT |
Abpcorp |
12 x 8 microwells |
EUR 472.8 |
 PrecisionX Multiplex gRNA Cloning Kit |
|
CAS9-GRNA-KIT |
SBI |
10 rxn |
EUR 534 |
|
|
) hspCas9 AAVS1 Safe Harbor Knock-in Donor (AAVS1-SA-puro-EF1-hspCas9) |
|
CAS620A-KIT |
SBI |
1 kit |
EUR 2582.4 |
|
|
|
Description: Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector), CAS640PR-1 (Junction PCR Primer Mix to confirm Cas9 integration site), and CAS9-PR-1 (PCR primers to confirm Cas9 expression) |
) PinPoint-FC System for Platform Cell Line Generation & Retargeting (includes PIN300A-1, FC200PA-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
|
PIN300A-KIT |
SBI |
1 Kit |
EUR 3357.6 |
|
|
) PinPoint-HR System for Platform Cell Line Generation & Retargeting (includes PIN400A-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
|
PIN400A-KIT |
SBI |
1 Kit |
EUR 3357.6 |
|
|
) PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, GE601A-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
|
PIN410A-KIT |
SBI |
1 Kit |
EUR 5202 |
|
|
) PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, CAS601A-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
|
PIN412A-KIT |
SBI |
1 Kit |
EUR 5202 |
|
|
 with goat anti-rabbit HRP secondary antibody) ExoAb Antibody Kit (CD9, CD63, CD81, Hsp70 antibodies, rabbit anti-human) with goat anti-rabbit HRP secondary antibody |
|
EXOAB-KIT-1 |
SBI |
25 ul each |
EUR 752.4 |
|
|
) mRNAExpress mRNA Synthesis kit (5 reactions) |
|
MR-KIT-1 |
SBI |
5 reactions |
EUR 1382.4 |
|
|
 AxioCam Erc5s rev 2, w/Accessory Kit |
|
ZV-Erc5sAC-Kit |
MiTeGen |
1 KIT |
EUR 1611 |
|
|
|
Description: AxioCam Erc5s rev 2, w/Accessory Kit- connection cable Y-USB 2.0.- HDMI cable to DVI-D- SD card- IR remote control |
 (Target 1)) Crbn sgRNA CRISPR Lentivector (Mouse) (Target 1) |
|
K3487502 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (Target 2)) Crbn sgRNA CRISPR Lentivector (Mouse) (Target 2) |
|
K3487503 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (Target 3)) Crbn sgRNA CRISPR Lentivector (Mouse) (Target 3) |
|
K3487504 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (Target 1)) Crbn sgRNA CRISPR Lentivector (Rat) (Target 1) |
|
K6667502 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (Target 2)) Crbn sgRNA CRISPR Lentivector (Rat) (Target 2) |
|
K6667503 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (Target 3)) Crbn sgRNA CRISPR Lentivector (Rat) (Target 3) |
|
K6667504 |
ABM |
1.0 ug DNA |
EUR 184.8 |
 (pPB-C-His)) CRBN Protein Vector (Mouse) (pPB-C-His) |
|
PV167882 |
ABM |
500 ng |
EUR 723.6 |
 (pPB-N-His)) CRBN Protein Vector (Mouse) (pPB-N-His) |
|
PV167883 |
ABM |
500 ng |
EUR 723.6 |
 (pPM-C-HA)) CRBN Protein Vector (Mouse) (pPM-C-HA) |
|
PV167884 |
ABM |
500 ng |
EUR 723.6 |
 (pPM-C-His)) CRBN Protein Vector (Mouse) (pPM-C-His) |
|
PV167885 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPB-C-His) |
|
PV167886 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPB-N-His) |
|
PV167887 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPM-C-HA) |
|
PV167888 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPM-C-His) |
|
PV167889 |
ABM |
500 ng |
EUR 723.6 |
 (pPB-C-His)) CRBN Protein Vector (Rat) (pPB-C-His) |
|
PV261642 |
ABM |
500 ng |
EUR 723.6 |
 (pPB-N-His)) CRBN Protein Vector (Rat) (pPB-N-His) |
|
PV261643 |
ABM |
500 ng |
EUR 723.6 |
 (pPM-C-HA)) CRBN Protein Vector (Rat) (pPM-C-HA) |
|
PV261644 |
ABM |
500 ng |
EUR 723.6 |
 (pPM-C-His)) CRBN Protein Vector (Rat) (pPM-C-His) |
|
PV261645 |
ABM |
500 ng |
EUR 723.6 |
 CRBN 3'UTR Luciferase Stable Cell Line |
|
TU004992 |
ABM |
1.0 ml |
EUR 2799.6 |
 Crbn 3'UTR Luciferase Stable Cell Line |
|
TU202771 |
ABM |
1.0 ml |
Ask for price |
 Crbn 3'UTR GFP Stable Cell Line |
|
TU252771 |
ABM |
1.0 ml |
Ask for price |
Crbn 3'UTR GFP Stable Cell Line |
|
TU154342 |
ABM |
1.0 ml |
Ask for price |
Crbn 3'UTR Luciferase Stable Cell Line |
|
TU104342 |
ABM |
1.0 ml |
Ask for price |
Human CRBN(Cereblon) ELISA Kit