You are Here
Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity
blocking peptide blood Blot ChiP coli recombinant colorimetric Control elektroporation elisa Insect Kangaroo Killifish Rabbit Raccoon Rat Reindeer Reptile Yeast

Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity

Non-steroidal anti-inflammatory medicine (NSAIDs) are a gaggle of medicine that are extensively used globally for the remedy of ache and irritation, and within the case of aspirin, for secondary prevention of heart problems. Chronic non-steroidal anti-inflammatory drug use is related to probably critical higher gastrointestinal opposed drug reactions (ADRs) together with peptic ulcer illness and gastrointestinal bleeding.
A number of scientific and genetic predisposing components have been recognized; nonetheless, genetic knowledge are contradictory. Further analysis is required to determine clinically related genetic and non-genetic markers predisposing to NSAID-induced peptic ulceration.

Is Perceived Athlete Leadership Quality Related to Inside Sacrifice and Perceived Performance in Team Sports? The Mediating Role of Team Identification

The research aimed to research the connection between athletes’ perceptions of athlete management high quality, staff identification, inside sacrifice, and efficiency. A complete of 299 gamers of collective sports activities (soccer, seaside soccer, basketball, volleyball; M age 19.05, SD = 5.10) participated via a cross-sectional design survey.
Data had been analyze
d utilizing structural equation modeling. Results spotlight the optimistic relationships between perceived high quality of athlete leaders, inside sacrifice, and perceived efficiency, and between inside sacrifice and perceived efficiency. Furthermore, inside sacrifice perceived by the athletes was a optimistic mediator between perceived athlete management high quality and perceived efficiency.
Also, staff identification was a optimistic mediator within the affiliation between inside sacrifice and perceived efficiency. These findings lengthen information concerning the athlete management high quality context. These outcomes can be helpful for additional analysis and implications in staff sports activities’ efficiency, as coaches and sports activities psychologists would have extra details about their groups’ perceptions of management high quality to attain optimistic outcomes in gamers’ inside sacrifice and efficiency. The findings additionally spotlight the significance of creating staff identification to enhance the relationships between perceived athlete management high quality, inside sacrifice, and perceived efficiency.

The Combined Effect of Safety Specific Transformational Leadership and Safety Consciousness on Psychological Well-Being of Healthcare Workers

Occupational well being analysisers have begun to understand that the psychological well-being of healthcare staff who’re offering remedy in opposition to COVID-19 is deteriorating. However, there’s minimal analysis performed on it, significantly within the context of management. The present research goals to fill this vital hole by figuring out crucial components that may improve the psychological well-being of healthcare staff.
We proposed that security particular transformational management enhances psychological well-being amongst healthcare staff, and COVID-19 perceived threat mediates this relationship. Furthermore, the protection conscientiousness of healthcare staff was proposed to be a boundary situation that enhances the destructive relationship between safety-specific transformational management and COVID-19 perceived threat.
Data had been collected from healthcare staff (N = 232) treating COVID-19 sufferers within the hospitals of Pakistan via well-established adopted questionnaires. The discriminant and convergent validity of the knowledge was examined via confirmatory issue evaluation by utilizing AMOS statistical bundle. The mediation and moderation hypotheses had been examined by utilizing PROCESS Macro by Hayes.
The outcomes confirmed that security particular transformational management enhances psychological well-being amongst healthcare staff, and COVID-19 perceived threat mediates this relationship. Moderation outcomes additionally confirmed that security conscientiousness moderates the connection between security particular transformational management and COVID-19 perceived threat. This research provides implications for each analysisers and practitioners.

Coating matching advice based mostly on improved fuzzy complete analysis and collaborative filtering algorithm

Coating matching design is one of the vital elements of ship coating course of design. The choice of coating matching is influenced by numerous components similar to marine corrosive setting, anti-corrosion interval and dealing circumstances. There are additionally variations within the coating efficiency necessities for various ship sorts and completely different coating elem

ents.

Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity
At current, the design of coating matching in shipyards is determined by the expertise of technologist, which isn’t conducive to the scientific administration of ship portray course of and the macro management of ship development price. Therefore, this paper proposes a hybrid algorithm of fuzzy complete analysis and collaborative filtering based mostly on consumer label enchancment (IFCE-CF).
Based on the analytic hierarchy course of (AHP), the analysis index system of coating matching is constructed, and the load calculation course of of fuzzy complete analysis is optimized by introducing the consumer label weight. The collaborative filtering algorithm based mostly on matrix decomposition is used to understand the correct advice of coating matching.
Historical coating course of knowledge of a shipyard between 2010 and 2020 are chosen to confirm the advice potential of the strategy within the paper. The outcomes present that utilizing the coating matching clever advice algorithm proposed on this paper, the basis imply sq. error is < 1.02 and the imply absolute error is < 0.75, the prediction accuracy is considerably higher than different analysis strategies, which proves the effectiveness of the strategy.

Measuring Youth Empowerment: An Item Response Theory Analysis of the Sociopolitical Control Scale for Youth

Sociopolitical management (SPC) has been recognized as a key ingredient of the intrapersonal element of psychological empowerment. The Sociopolitical Control Scale (SPCS) is a extensively used measure and has been modified to be used amongst youth (SPCS-Y). In gentle of the rising curiosity in SPC amongst youth inside community-based analysis, this research utilized merchandise response principle (IRT) to look at the psychometric properties of the SPCS-Y and to discover a quick model.
Data had been collected between 2006 and 2013 from a comfort pattern of highschool college students (N = 1,808), situated in a midsized, economically deprived city neighborhood within the northeastern United States. Findings point out that the 2 subscales, management competence, and coverage management, had been unidimensional and gadgets functioned properly.

Goat Anti-Mouse IgG(H+L) Alexa Fluor 594–conjugated
S0005 200ul
EUR 376

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 594–conjugated
S0006 200ul
EUR 376

Donkey Anti-Goat IgG (H+L), Alexa Fluor® 594 Conjugated
Ab8011-001 1mg
EUR 334

Donkey anti Goat IgG (H + L) (Fab 2) (Alexa Fluor 594)
43R-ID012AF 300 ug
EUR 410
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594)

SAM FCM (Alexa Fluor 647)
abx098902-100tests 100 tests
EUR 1233

SAM FCM (Alexa Fluor 488)
abx098904-60tests 60 tests
EUR 1358

EGFR antibody (Alexa Fluor 488)
61R-E109BAF 125 ug
EUR 706
Description: Mouse monoclonal EGFR antibody (Alexa Fluor 488)

Anti-CD40 antibody (Alexa-fluor 488)
STJ170000 100 µg
EUR 393
Description: CD40 (48 to 50 kDa) is a transmembrane glycoprotein mainly expressed on the surface of B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily, which includes the low affinity nerve growth factor (NGF) receptor and CD95/Fas. CD40 is the receptor for CD40 ligand. CD40L (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40, predominantly on activated CD4+ T cells. Following interaction with CD40 ligand, CD40 mediates a number of major immunoregulatory functions, central to the control of thymus dependent humoral immunity and may be critical in the development of cell mediated immune responses. Other biological actions include B cell homotypic adhesion, proliferation, immunoglobulin isotype switch, and secretion. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin

Anti-LAMP3 antibody (Alexa-fluor 488)
STJ170004 100 µg
EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-LAMP3 antibody (Alexa-fluor 546)
STJ170005 100 µg
EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-LAMP3 antibody (Alexa-fluor 647)
STJ170006 100 µg
EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-IL3RA antibody (Alexa-fluor 488)
STJ170009 100 µg
EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 546)
STJ170010 100 µg
EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 647)
STJ170011 100 µg
EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-CD207 antibody (Alexa-fluor 488)
STJ170014 100 µg
EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 546)
STJ170015 100 µg
EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 647)
STJ170016 100 µg
EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-IL7R antibody (Alexa-fluor 488)
STJ170020 100 µg
EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 546)
STJ170021 100 µg
EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 647)
STJ170022 100 µg
EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-RPSA Alexa Fluor® 488
A4-829-C100 0.1 mg
EUR 310

Anti-Hu CD16 Alexa Fluor® 488
A4-646-T100 100 tests
EUR 269

Goat anti Mouse IgG1 (Alexa Fluor 488)
43R-1649 500 ug
EUR 570
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

Alpha Fluor™ 594 C5 Maleimide
1891 1 mg
EUR 219

Streptavidin-Alexa594 (Alexas fluor 594) conjugate
SV-A594-100 100 tests
EUR 225

Rabbit Anti-Rat IgG (H+L)-Alexa 594 Fluor conjugate (adsorbed with human IgG)
50337 0.5 ml
EUR 225

Alpha Fluor™ 532 acid [equivalent to Alexa Fluor™ 532 acid]
1795 10 mg
EUR 393

AF350-streptavidin conjugate [Streptavidin, Alexa Fluor™ 350 Conjugate]
16890 1 mg
EUR 176

AF488-streptavidin conjugate [Streptavidin, Alexa Fluor™ 488 Conjugate]
16891 1 mg
EUR 176

AF350 Phalloidin [equivalent to Alexa Fluor® 350 phalloidin]
23150 300 Tests
EUR 306

AF488 Phalloidin [equivalent to Alexa Fluor® 488 phalloidin]
23153 300 Tests
EUR 306

Anti-Hu CD72 Alexa Fluor® 488
A4-310-T100 100 tests
EUR 269

Anti-Bov CD9 Alexa Fluor® 488
A4-354-C100 0.1 mg
EUR 269

Anti-Hu CD30 Alexa Fluor® 700
A7-455-T100 100 tests
EUR 269

Anti-Hu CD94 Alexa Fluor® 700
A7-727-T100 100 tests
EUR 269

Anti-Hu CD56 Alexa Fluor® 700
A7-789-T100 100 tests
EUR 269

Donkey anti Goat IgG (H + L) (Alexa Fluor 647)
43R-ID028AF 500 ug
EUR 430
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 647)
43R-ID060AF 300 ug
EUR 425
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647)

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 647–conjugated
S0013 200ul
EUR 304

Goat Anti-Mouse IgG(H+L) Alexa Fluor 647–conjugated
S0014 200ul
EUR 304

Goat Anti-Mouse IgG(H+L) Alexa Fluor 488–conjugated
S0017 200ul
EUR 304

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 488–conjugated
S0018 200ul
EUR 304

Donkey Anti-Rabbit IgG (H+L), Alexa Fluor® 488 Conjugated
Ab8032-001 0.5mg
EUR 435

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 488
A4-686-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 488
A4-712-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 488
A4-730-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 488
A4-737-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647
A6-686-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 647
A6-712-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647
A6-730-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647
A6-737-C100 0.1 mg
EUR 269

Anti-LAMP3 (human) Monoclonal Antibody (104G4) (Alexa Fluor® 488)
M09406 100ug
EUR 565
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Anti-Langerin (human) Monoclonal Antibody (DCGM4/122D5) (Alexa Fluor® 488)
M02316 100ug
EUR 580
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)
50336 0.5 ml
EUR 225

Recombinant (E.Coli) Human Thyrostimulin Beta
RP-594 10 ug
EUR 286

PDL1 Recombinant Protein
96-594 0.1 mg
EUR 595.25
Description: Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

FGF2 Recombinant Protein
91-594 0.05 mg
EUR 542.75
Description: Fibroblast growth factor 2(FGF2) is a secreted protein and belongs to the heparin-binding growth factors family. FGF2 is produced by epithelial, tumor and other cell types. It involved in developmental processes and regulates differentiation, proliferation, and migration, FGF2 is a critical factor for growing embryonic stem cells in culture without inducing differentiation. FGF2 has a high affinity for heparan sulfate and binding is a step in the FGF basic activation of FGFR tyrosine kinase.

CD83 Recombinant Protein
92-594 0.05 mg
EUR 401
Description: CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. It contains one Ig-like V-type (immunoglobulin-like) domain, the soluble CD83 has the opposite effect and has an immune inhibitory capacity. Due to its immune inhibitory function, CD83 may play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.

BBT-594
B2114-25
EUR 631

BBT-594
B2114-5
EUR 196

Anti-Cytokeratins Alexa Fluor488
A4-108-C025 0.025 mg
EUR 175

Anti-Cytokeratins Alexa Fluor488
A4-108-C100 0.1 mg
EUR 310

Anti-PSMA Alexa Fluor488
A4-539-C025 0.025 mg
EUR 227

Anti-PSMA Alexa Fluor488
A4-539-C100 0.1 mg
EUR 414

Anti-FoxP3 Alexa Fluor488
A4-601-C025 0.025 mg
EUR 201

Anti-FoxP3 Alexa Fluor488
A4-601-C100 0.1 mg
EUR 362

Anti-Phosphotyrosine Alexa Fluor647
A6-263-C025 0.025 mg
EUR 154

Anti-Phosphotyrosine Alexa Fluor647
A6-263-C100 0.1 mg
EUR 269

Anti-LCK Alexa Fluor647
A6-269-C025 0.025 mg
EUR 206

Anti-LCK Alexa Fluor647
A6-269-C100 0.1 mg
EUR 373

Anti-FoxP3 Alexa Fluor647
A6-601-C025 0.025 mg
EUR 201

Anti-FoxP3 Alexa Fluor647
A6-601-C100 0.1 mg
EUR 362

Alpha Fluor™ 488 amine
1705 1 mg
EUR 306

Alpha Fluor™ 488 Hydroxylamine
1900 1 mg
EUR 306

Tide Fluor 2-LL-37
H-8286.0100 0.1mg
EUR 312
Description: Sum Formula: C205H340N60O53+dye

Tide Fluor 2-LL-37
H-8286.0500 0.5mg
EUR 1017
Description: Sum Formula: C205H340N60O53+dye

Anti-Cytokeratin 18 Alexa Fluor488
A4-106-C025 0.025 mg
EUR 186

Anti-Cytokeratin 18 Alexa Fluor488
A4-106-C100 0.1 mg
EUR 331

Anti-Cytokeratin 19 Alexa Fluor488
A4-120-C025 0.025 mg
EUR 186

Anti-Cytokeratin 19 Alexa Fluor488
A4-120-C100 0.1 mg
EUR 331

Anti-Ki-67 Alexa Fluor488
A4-155-T025 25 tests
EUR 154

Anti-Ki-67 Alexa Fluor488
A4-155-T100 100 tests
EUR 269

Anti-Hu CD45 Alexa Fluor488
A4-160-T100 100 tests
EUR 269

Anti-Hu CD193 Alexa Fluor488
A4-161-T100 100 tests
EUR 269

Anti-Hu CD279 Alexa Fluor488
A4-176-T100 100 tests
EUR 269

Anti-Hu CD43 Alexa Fluor488
A4-220-T025 25 tests
EUR 154

Anti-Hu CD43 Alexa Fluor488
A4-220-T100 100 tests
EUR 269

Anti-Hu CD44 Alexa Fluor488
A4-221-T025 25 tests
EUR 154

Anti-Hu CD44 Alexa Fluor488
A4-221-T100 100 tests
EUR 269

Anti-Hu CD45 Alexa Fluor488
A4-222-T025 25 tests
EUR 154

Anti-Hu CD45 Alexa Fluor488
A4-222-T100 100 tests
EUR 269

Anti-Hu CD55 Alexa Fluor488
A4-230-T025 25 tests
EUR 154

Anti-Hu CD55 Alexa Fluor488
A4-230-T100 100 tests
EUR 269

Anti-Hu CD50 Alexa Fluor488
A4-266-T025 25 tests
EUR 154

Anti-Hu CD50 Alexa Fluor488
A4-266-T100 100 tests
EUR 269

Anti-Hu CD31 Alexa Fluor488
A4-273-T025 25 tests
EUR 154

Anti-Hu CD31 Alexa Fluor488
A4-273-T100 100 tests
EUR 269

Anti-Hu CD147 Alexa Fluor488
A4-274-T025 25 tests
EUR 154

Anti-Hu CD147 Alexa Fluor488
A4-274-T100 100 tests
EUR 269

Anti-Hu CD34 Alexa Fluor488
A4-297-T025 25 tests
EUR 154

Anti-Hu CD34 Alexa Fluor488
A4-297-T100 100 tests
EUR 269

Anti-Hu CD105 Alexa Fluor488
A4-298-T025 25 tests
EUR 154

Anti-Hu CD105 Alexa Fluor488
A4-298-T100 100 tests
EUR 269

Anti-Hu CD41 Alexa Fluor488
A4-309-T025 25 tests
EUR 154

Anti-Hu CD41 Alexa Fluor488
A4-309-T100 100 tests
EUR 269

Anti-Hu CD72 Alexa Fluor488
A4-310-T025 25 tests
EUR 154

Anti-Hu CD63 Alexa Fluor488
A4-343-T025 25 tests
EUR 154

Anti-Hu CD63 Alexa Fluor488
A4-343-T100 100 tests
EUR 269

Anti-Hu CD13 Alexa Fluor488
A4-396-T025 25 tests
EUR 154

Anti-Hu CD13 Alexa Fluor488
A4-396-T100 100 tests
EUR 269

Anti-HLA-G Alexa Fluor488
A4-431-C025 0.025 mg
EUR 217

Anti-HLA-G Alexa Fluor488
A4-431-C100 0.1 mg
EUR 394

Anti-HLA-G Alexa Fluor488
A4-437-C025 0.025 mg
EUR 217

Anti-HLA-G Alexa Fluor488
A4-437-C100 0.1 mg
EUR 394

Anti-Hu CD300a Alexa Fluor488
A4-501-T100 100 tests
EUR 269

Anti-HLA-A2 Alexa Fluor488
A4-556-T025 25 tests
EUR 154

Anti-HLA-A2 Alexa Fluor488
A4-556-T100 100 tests
EUR 269

Anti-CD3 zeta Alexa Fluor488
A4-568-C100 0.1 mg
EUR 269

Anti-Ms CD8a Alexa Fluor488
A4-579-C025 0.025 mg
EUR 139

Anti-Ms CD8a Alexa Fluor488
A4-579-C100 0.1 mg
EUR 238

Anti-Hu CD326 Alexa Fluor488
A4-582-T100 100 tests
EUR 269

Anti-Hu CD3 Alexa Fluor488
A4-631-T100 100 tests
EUR 269

Anti-Hu CD16 Alexa Fluor488
A4-646-T025 25 tests
EUR 154

Anti-Hu CD150 Alexa Fluor488
A4-660-T100 100 tests
EUR 269

Anti-Hu CD107a Alexa Fluor488
A4-671-T025 25 tests
EUR 154

Anti-Hu CD107a Alexa Fluor488
A4-671-T100 100 tests
EUR 269

Anti-Hu CD107b Alexa Fluor488
A4-672-T025 25 tests
EUR 154

Anti-Hu CD107b Alexa Fluor488
A4-672-T100 100 tests
EUR 269

Anti-Hu CD73 Alexa Fluor488
A4-675-T100 100 tests
EUR 269

Anti-Hu CD11b Alexa Fluor488
A4-681-T025 25 tests
EUR 154

Anti-Hu CD11b Alexa Fluor488
A4-681-T100 100 tests
EUR 269

Anti-Hu CD35 Alexa Fluor488
A4-703-T100 100 tests
EUR 269

Anti-Hu CD305 Alexa Fluor488
A4-713-T100 100 tests
EUR 269

Anti-Hu CD161 Alexa Fluor488
A4-729-T100 100 tests
EUR 269

Anti-Hu CD144 Alexa Fluor488
A4-770-T100 100 tests
EUR 269

Anti-HLA-ABCE Alexa Fluor488
A4-813-C100 0.1 mg
EUR 373

Anti-Ki-67 Alexa Fluor647
A6-155-T025 25 tests
EUR 154

Anti-Ki-67 Alexa Fluor647
A6-155-T100 100 tests
EUR 269

Anti-Hu CD45 Alexa Fluor647
A6-160-T100 100 tests
EUR 269

Anti-Hu CD193 Alexa Fluor647
A6-161-T100 100 tests
EUR 269

Anti-Hu CD279 Alexa Fluor647
A6-176-T100 100 tests
EUR 269

Anti-Hu CD273 Alexa Fluor647
A6-178-T100 100 tests
EUR 269

Anti-Hu CD231 Alexa Fluor647
A6-200-T100 100 tests
EUR 269

Anti-Hu CD9 Alexa Fluor647
A6-208-T025 25 tests
EUR 154

Anti-Hu CD9 Alexa Fluor647
A6-208-T100 100 tests
EUR 269

Anti-Hu CD45 Alexa Fluor647
A6-222-T025 25 tests
EUR 154

Anti-Hu CD45 Alexa Fluor647
A6-222-T100 100 tests
EUR 269

Anti-Hu CD45RB Alexa Fluor647
A6-224-T025 25 tests
EUR 154

Anti-Hu CD45RB Alexa Fluor647
A6-224-T100 100 tests
EUR 269

Anti-Hu CD55 Alexa Fluor647
A6-230-T025 25 tests
EUR 154

Anti-Hu CD55 Alexa Fluor647
A6-230-T100 100 tests
EUR 269

Anti-Hu CD59 Alexa Fluor647
A6-233-T025 25 tests
EUR 154

Anti-Hu CD59 Alexa Fluor647
A6-233-T100 100 tests
EUR 269

Anti-Hu CD71 Alexa Fluor647
A6-235-T025 25 tests
EUR 154

Anti-Hu CD71 Alexa Fluor647
A6-235-T100 100 tests
EUR 269

Anti-Hu CD21 Alexa Fluor647
A6-306-T025 25 tests
EUR 154

Anti-Hu CD21 Alexa Fluor647
A6-306-T100 100 tests
EUR 269

Anti-Hu CD177 Alexa Fluor647
A6-314-T025 25 tests
EUR 154

Anti-Hu CD177 Alexa Fluor647
A6-314-T100 100 tests
EUR 269

Anti-Hu CD222 Alexa Fluor647
A6-315-T025 25 tests
EUR 154

Anti-Hu CD222 Alexa Fluor647
A6-315-T100 100 tests
EUR 269

Anti-Hu CD30 Alexa Fluor647
A6-455-T025 25 tests
EUR 154

Anti-Hu CD30 Alexa Fluor647
A6-455-T100 100 tests
EUR 269

Anti-gamma-Tubulin Alexa Fluor647
A6-465-C025 0.025 mg
EUR 217

Anti-gamma-Tubulin Alexa Fluor647
A6-465-C100 0.1 mg
EUR 394

Anti-Hu CD264 Alexa Fluor647
A6-519-C100 0.1 mg
EUR 269
Most gadgets functioned significantly properly at low and reasonable ranges of the assemble, however just a few had been in a position to seize increased ranges of the assemble. Based on our IRT analyses of the efficiency of gadgets on the subscales, we chosen gadgets to create a quick model of the SPCS-Y (BSPCS-Y) and carried out structural equation modeling for additional examination. Results present empirical proof to assist the reliability and validity of the SPCS-Y and recommend a quick model based mostly on high-performing gadgets is feasible.
Share
Facebook Twitter Pinterest Linkedin

Related Posts

Leave a Reply

Your email address will not be published.

Pages